A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness U Joshi, A Pearson, JE Evans, H Langlois, N Saltiel, J Ojo, N Klimas, ... Brain, behavior, and immunity 81, 545-559, 2019 | 49 | 2019 |
Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model U Joshi, JE Evans, A Pearson, N Saltiel, A Cseresznye, T Darcey, J Ojo, ... Neurotoxicology 79, 84-94, 2020 | 36 | 2020 |
Repeated unpredictable stress and social isolation induce chronic HPA axis dysfunction and persistent abnormal fear memory M Algamal, AJ Pearson, C Hahn-Townsend, I Burca, M Mullan, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 104, 110035, 2021 | 31 | 2021 |
Impact of repetitive mild traumatic brain injury on behavioral and hippocampal deficits in a mouse model of chronic stress M Algamal, N Saltiel, AJ Pearson, B Ager, I Burca, B Mouzon, ... Journal of neurotrauma 36 (17), 2590-2607, 2019 | 27 | 2019 |
Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma J Ojo, M Eisenbaum, B Shackleton, C Lynch, U Joshi, N Saltiel, A Pearson, ... Neurobiology of disease 150, 105237, 2021 | 20 | 2021 |
Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients A Pearson, R Ajoy, G Crynen, JM Reed, M Algamal, M Mullan, D Purohit, ... BMC neurology 20, 1-20, 2020 | 20 | 2020 |
Influence of traumatic brain injury on extracellular tau elimination at the blood–brain barrier M Eisenbaum, A Pearson, A Gratkowski, B Mouzon, M Mullan, F Crawford, ... Fluids and Barriers of the CNS 18, 1-13, 2021 | 18 | 2021 |
Exogenous lipase administration alters gut microbiota composition and ameliorates Alzheimer’s disease-like pathology in APP/PS1 mice A Menden, D Hall, C Hahn-Townsend, CA Broedlow, U Joshi, A Pearson, ... Scientific reports 12 (1), 4797, 2022 | 16 | 2022 |
ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytes M Eisenbaum, A Pearson, C Ortiz, M Mullan, F Crawford, J Ojo, ... Glia 72 (1), 184-205, 2024 | 14 | 2024 |
Deletion of PTEN in microglia ameliorates chronic neuroinflammation following repetitive mTBI A Pearson, C Ortiz, M Eisenbaum, C Arrate, M Browning, M Mullan, ... Molecular and Cellular Neuroscience 125, 103855, 2023 | 7 | 2023 |
Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI … C Ortiz, A Pearson, R McCartan, S Roche, N Carothers, M Browning, ... Journal of Neuroinflammation 21 (1), 130, 2024 | 5 | 2024 |
Repetitive head trauma and apoE4 induce chronic cerebrovascular alterations that impair tau elimination from the brain M Eisenbaum, A Pearson, C Ortiz, M Koprivica, A Cembran, M Mullan, ... Experimental Neurology 374, 114702, 2024 | 5 | 2024 |
PPARγ activation ameliorates cognitive impairment and chronic microglial activation in the aftermath of r-mTBI A Pearson, M Koprivica, M Eisenbaum, C Ortiz, M Browning, T Vincennie, ... Journal of Neuroinflammation 21 (1), 194, 2024 | 2 | 2024 |
Human amnionic progenitor cell secretome mitigates the consequence of traumatic optic neuropathy in a mouse model R McCartan, A Gratkowski, M Browning, C Hahn-Townsend, S Ferguson, ... Molecular Therapy Methods & Clinical Development 29, 303-318, 2023 | 2 | 2023 |
NADPH oxidase (NOX2)-mediated regulation of microglial NLRP3 inflammasome activation in traumatic brain injury J Laabei, G Vegliante, NR Strogulski, S Threja, C Douglas, M Hanscom, ... EUROPEAN JOURNAL OF IMMUNOLOGY 54, 1369-1369, 2024 | | 2024 |
ASTROCYTE-DERIVED PATHOGENIC TAU PROPAGATES NEUROINFLAMMATION AND NEURODEGENERATION FOLLOWING R-MTBI VIA REMODELING OF THE ASTROCYTE SECRETOME C Ortiz, A Pearson, J Reed, F Crawford, J Ojo JOURNAL OF NEUROTRAUMA 40 (15-16), A87-A87, 2023 | | 2023 |
GENETIC OVEREXPRESSION AND ACTIVATION OF MICROGLIAL PPARgamma AMELIORATES CHRONIC NEUROINFLAMMATION AND REACTIVE GLIOSIS FOLLOWING REPETITIVE MILD TRAUMATIC BRAIN INJURY A Pearson, M Koprivica, C Ortiz, M Browning, F Crawford, J Ojo JOURNAL OF NEUROTRAUMA 40 (15-16), A58-A58, 2023 | | 2023 |
TAU PROCESSING BY ASTROCYTES IS IMPAIRED AFTER TRAUMATIC BRAIN INJURY IN AN APOE ISOFORM-DEPENDENT MANNER M Eisenbaum, A Pearson, J Ojo, F Crawford, C Bachmeier JOURNAL OF NEUROTRAUMA 39 (11-12), A86-A87, 2022 | | 2022 |
TAU ASTROGLIOPATHY IN THE AFTERMATH OF REPETITIVE MILD TRAUMATIC BRAIN INJURY C Ortiz, A Pearson, R McCartan, S Roche, B Mouzon, M Mullan, E Mufson, ... JOURNAL OF NEUROTRAUMA 39 (11-12), A100-A101, 2022 | | 2022 |
CO-EXPRESSION META-ANALYSIS OF YOUNG AND AGED MICROGLIA IDENTIFIES UPSTREAM REGULATORS DRIVING NEUROINFLAMMATION AND NEURODEGENERATION IN THE ACUTE TO CHRONIC AFTERMATH OF … A Pearson, C Ortiz, R McCartan, F Crawford, J Ojo JOURNAL OF NEUROTRAUMA 39 (11-12), A86-A86, 2022 | | 2022 |